When choosing or editing a gaming or anime PFP, focus on a clear silhouette and...

https://romeo-wiki.win/index.php/How_Do_I_Pick_a_Game_Character_That_Stays_Recognizable_as_a_Tiny_Icon%3F

When choosing or editing a gaming or anime PFP, focus on a clear silhouette and high contrast so your icon pops even super small. Crop close to the face and keep the background simple to avoid clutter